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    Beta-blockers Plus: A Fixed-dose Combination Quiz

    Combinations of fixed-dose antihypertensive agents have become popular in the treatment of high blood pressure. This is a spot-check quiz on features, benefits, and the dual MOA of one specific combination.

    1. Which of the following choices is/are correct in regard to coadministering antihypertensives from two different classes (you may choose more than one answer):

    A. Combining 2 antihypertensive agents from different classes will lower blood pressure more than maximizing a single agent (proceeding with escalating doses of monotherapy).

    B. When combinations are used, there are fewer adverse events than with escalating doses of single agents.

    C. Patient medication adherence is improved with fixed-dose combination agents.

    D. Available fixed-dose combination formulations are proven pharmacologically compatible.

    Answer, discussion, and next question>>

    Gregory W. Rutecki, MD
    Dr Rutecki is with the Cleveland Clinic National Consultation Service.


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